Isolated Adrenocorticotropin Deficiency Associated with Delirium and Takotsubo Cardiomyopathy

Table 2

Hormonal data in detailed examination.

(a) Basal levels

ACTH	8.4 pg/mL (7.2–63.3)
Cortisol	2.2 μg/dL (4.0–18.3)
TSH	1.52 μIU/mL (0.55–4.78)
FT3	2.38 pg/mL (2.13–4.07)
FT4	1.89 ng/dL (0.89–1.76)
Plasma renin activity	0.3 ng/mL/hr (0.3–2.9)
Plasma aldosterone	76.8 pg/mL (29.9–159.0)
Urine free cortisol	8.7 μg/day (11.2–80.3)
Urine metanephrine	0.03 mg/day (0.04–0.19)
Urine normetanephrine	0.16 mg/day (0.09–0.33)

Figures in parentheses indicate the normal range.

(b) Rapid ACTH test

Time (min)	0	30	60
Cortisol (𝜇g/dL)	5.4	14.1	16.8

(c) CRH, LHRH, GRH test

Time (min)	0	30	60	90	120
ACTH (pg/mL)	7.8	14.3	11.7	9.2	8.3
Cortisol (𝜇g/dL)	5.7	6.4	5.7	5.4	5.4
LH (mIU/mL)	19.92	64.31	68.04	66.7	62.75
FSH (mIU/mL)	64.50	75.37	79.86	82.44	86.36
GH (ng/mL)	0.64	8.72	12.3	12.1	4.66

(d) Continuous ACTH test

Day	1	2	3	4	5	6	7
Urine free cortisol (μg/day)	5.8	7.0	7.5	99.8	546.0	866.0	2950.0