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Case Reports in Endocrinology
Volume 2013 (2013), Article ID 174593, 4 pages
http://dx.doi.org/10.1155/2013/174593
Case Report

Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient

1Department of Pediatrics, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, 3535 Market Street, Room 1562, Philadelphia, PA 19104, USA
2Division of Pediatric Endocrinology, St. Christopher's Hospital for Children, 3601 A. Street, Philadelphia, PA 19134, USA
3Division of Pediatric Endocrinology, Monmouth Medical Children's Hospital, 180 Avenue at the Commons, Suite 7B, Shrewsbury, NJ 07702, USA
4Department of Pathology, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
5Department of General Surgery, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA

Received 13 March 2013; Accepted 19 May 2013

Academic Editors: C. Capella, M. Demura, N. Islam, and M. P. Kane

Copyright © 2013 Elizabeth Isaacoff et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with tumors in pediatric populations or in the adrenal gland. We present a case of malignant AN in a pediatric patient with a nonmalignant, functional adrenocortical tumor.