Table of Contents Author Guidelines Submit a Manuscript

An erratum for this article has been published. To view the erratum, please click here.

Case Reports in Endocrinology
Volume 2013, Article ID 465376, 4 pages
Case Report

Hypogonadotropic Hypogonadism Associated with Hereditary Hemorrhagic Telengiectasia

1Neurology Unit, “S. Maria del Pozzo” Hospital, Somma Vesuviana, 80049 Naples, Italy
2Center for Rare Diseases, “Clinica Medica Frugoni”, University Hospital of Bari, 70124 Bari, Italy
3Unit of Endocrinology, University Hospital of Bari, 70124 Bari, Italy

Received 23 February 2013; Accepted 18 March 2013

Academic Editors: M. A. Boyanov, O. Isozaki, M. P. Kane, and L. Mastrandrea

Copyright © 2013 Scarano Valentina et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 65-year-old man was referred to our clinic for the rehabilitation of right hemiparesis caused by ischaemic stroke. Hypertension, postphlebitic syndrome of lower limbs, frequent nose bleeding, and anemia were present in his history; in his adolescence, he was treated for idiopathic hypogonadotropic hypogonadism. Further investigations have revealed also microsomia, suggesting a clinical diagnosis of Kallmann syndrome, that is, an association, possible in males and females, of hypogonadotropic hypogonadism with olfactory deficits. A definite diagnosis of hereditary hemorrhagic telangiectasia was made based on clinical criteria and confirmed by genetic analysis.