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Case Reports in Endocrinology
Volume 2013, Article ID 735489, 5 pages
Case Report

Monitoring Patient Improvement Parameters following Pasireotide Treatment in Cushing’s Disease

1Northwest Pituitary Center, 3303 SW Bond Avenue, Portland, OR 97239, USA
2Department of Neurosurgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
3Department of Internal Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA

Received 2 August 2013; Accepted 18 September 2013

Academic Editors: M. Demura, O. Isozaki, and M. P. Kane

Copyright © 2013 Chris Yedinak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cushing’s disease (CD) is a disorder in which chronic excess adrenocorticotropic hormone production is associated with multiple comorbidities and diminished quality of life. Postsurgical monitoring is important, and newer therapies are available for the management of surgical failure or disease recurrence. In this clinical case, we illustrate the importance of the nursing role in long-term management of CD, particularly as nurses may be the first point of contact for patients with CD. Alertness to disease signs and symptoms is crucial for timely diagnosis and improved outcomes. Successful therapy for CD requires careful monitoring of hormonal control, metabolic parameters, and therapy complications. Ongoing management requires lifelong monitoring of metabolic parameters, of side effects of treatment, and of signs of disease recurrence. Appropriate referrals may be required to facilitate overall outcomes and patient wellbeing. This patient was enrolled in a Phase III trial that was registered in the USA with