Ovarian Leydig Cell Hyperplasia: An Unusual Case of Virilization in a Postmenopausal Woman
Figure 1
Whole-slide sections of left (a) and right (b) ovaries display multiple eosinophilic nodules of Leydig cells (arrows). Immunohistochemistry for inhibin A highlights the nodules and identifies additional small clusters of Leydig cells (c, whole-slide section, right ovary). The nodules are composed of Leydig cells, which are polygonal with abundant granular eosinophilic cytoplasm and large vesicular nuclei (d, H&E, 400x). The Leydig cells display strong cytoplasmic staining with inhibin A (e, 400x).
