Multifactorial Hypercalcemia and Literature Review on Primary Hyperparathyroidism Associated with Lymphoma

Table 2

The literature review of reported cases of hypercalcemia and malignancy.

Study	Basic study features	Cause of hypercalcemia
Strodel et al. [9]	18 patients with malignancy and hypercalcemia	All patients had PHPT as the only cause of hypercalcemia.
Hutchesson et al. [10]	47 patients with malignancy and hypercalcemia	3 of 47 patients had PHPT as the cause of hypercalcemia. No cases of 2 causes of elevated calcium levels.
Owen et al. [11]	2 cases of primary cutaneous lymphomas and hypercalcemia	Both cases were found to have PHPT as the only cause of hypercalcemia
Albès et al. [12]	A case of T-cell lymphoma and hypercalcemia	Hypercalcemia caused by PHPT only
Aguilar-Bernier et al. [13]	Lymphomatoid papulosis	Hypercalcemia caused by PHPT only
Gallacher et al. [14]	Hypercalcemia did not resolve after removal of parathyroid adenoma which prompted further workup and the patient was found to have malignancy in the manubrium sterni	One case with two coexisting mechanisms of hypercalcemia—PHPT and PTHrP mediated
Luceri and Haenel [15]	Hypercalcemia did not resolve after removal of parathyroid adenoma which prompted further workup and the patient was found to have diffuse large B-cell lymphoma	One case with two coexisting mechanisms of hypercalcemia—PHPT and 1,25-dihydroxyvitamin D mediated