Primary Hyperparathyroidism and Hyperthyroidism in a Patient with Myotonic Dystrophy: A Case Report and Review of the Literature

Table 2

Hyperparathyroidism associated with MD: review of the literature.

Authors	Number of cases	Age/sex	Hormonal status	Clinical features	Calcium mmol/L	Phosphate mmol/L	PTH pg/mL	Treatment
Ørngreen et al. 2012 [1]	97	25–65/4M-12F	16: hyperparathyroidism	Symptoms in 1 case	High: 2 cases; 2.67 ± 0.03	Low: 7 cases; 0.67 ± 0.02	High: 16 cases (16%)	Parathyroidectomy in 1 case
Molina et al. 1996 [2]	1	—	Hyperthyroidism and hyperparathyroidism	No symptoms	—	—	—	Parathyroid adenoma extirpation, subtotal thyroidectomy
Rosenberg et al. 1988 [3]	4	44-12-42-45/F	1: hyperparathyroidism (parathyroid hyperplasia); 1: hyperparathyroidism and neurofibromatosis; 2: hyperparathyroidism and thyroid carcinoma	Weakness; Hypercalcemia	High	—	High	Parathyroid adenoma extirpation
Passeri et al. 2013 [27]	44	44–56/M	8: hyperparathyroidism	2: hypercalcemia hypophosphatemia	2.37	0.74	High > 65 pg/mL	—
Harada et al. 1987 [28]	2	55–57/M-M	Hyperparathyroidism; Parathyroid adenoma	No symptoms; Hypercalcemia	High	—	High	Parathyroid adenoma extirpation
Kinoshita et al. 1997 [29]	24	36–58/6M-7F	13: pseudohypoparathyroidism	Hypocalcemia	2.05	1.005	1013.9	—
Garcia Delgado and Ruiz Galiana 1988 [30]	1	40/M	Hyperparathyroidism; Parathyroid adenoma	Bone pain	—	—	—	Parathyroid adenoma extirpation
Middleton et al. 1989 [31]	1	52/F	Hyperparathyroidism; Parathyroid hyperplasia	Symptomatic hypercalcemia	High: 4.05	0.35	5070	Parathyroidectomy
Downie and Jepson 1990 [32]	1	56/F	Hyperparathyroidism	No symptoms; Hypercalcemia	High: 2.73	—	180	—
Bell et al. 1994 [33]	1	56/F	Hyperparathyroidism; Parathyroid adenoma	Hypercalcemia	High	Low	High	Parathyroid adenoma extirpation