Treatment of Ipilimumab Induced Graves’ Disease in a Patient with Metastatic Melanoma

Table 1

Thyroid function tests changes during treatments.

	Before ipilimumab	1 month after ipilimumab	Ipilimumab held, methimazole started	2 months after ipilimumab	Ipilimumab restarted	1 month after restarting ipilimumab	1 month after total thyroidectomy
TSH (0.55–4.78 mUJ/mL)	1.561	0.009	<0.008	0.015	0.015	0.071	0.892
Free T4 (0.89–1.76 ng/dL)	1.42	3.38	3.64	1.36	1.31	1.01	1.47
Free T3 (2/3–4.2 pg/mL)		8.8	9.8	4.1	4.1	3.6
TSI (thyroid stimulating immunoglobulin) (<140%)		368