The Biochemical Profile of Familial Hypocalciuric Hypercalcemia and Primary Hyperparathyroidism during Pregnancy and Lactation: Two Case Reports and Review of the Literature

Table 1

Summary of serum and urine biochemistry in patients 1 and 2 prior to pregnancy, during pregnancy, and during lactation.

	Patient 1 (FHH)	Patient 2 (PHPT)	Reference range
Prior to pregnancy
Albumin adjusted calcium (mmol/L)	2.61 mmol/L	n/a	2.10–2.55 mmol/L
PTH (ng/L)	33 ng/L	n/a	13–54 ng/L
CCCR (%)	0.79%	n/a	<2% = possible hypocalciuria; <1% = hypocalciuria
Pregnancy
Albumin adjusted calcium (mmol/L)	2.59 mmol/L	2.97 mmol/L	2.10–2.55 mmol/L
PTH (ng/L)	46 ng/L	52 ng/L	13–54 ng/L
CCCR (%)	1.99%	2.67%	n/d
Lactation
Albumin adjusted calcium (mmol/L)	2.53 mmol/L	2.96 mmol/L	2.10–2.55 mmol/L
CCCR (%)	n/a	0.89%	n/d

n/a = not available.
n/d = not defined.
Reference ranges are for nonpregnant and nonlactating patients.