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Case Reports in Endocrinology
Volume 2016 (2016), Article ID 3240585, 3 pages
http://dx.doi.org/10.1155/2016/3240585
Case Report

Amyloid Goiter Secondary to Ulcerative Colitis

1Division of Endocrinology and Metabolism, Department of Internal Medicine, Suleyman Demirel University, School of Medicine, 32200 Isparta, Turkey
2Department of General Surgery, Suleyman Demirel University, School of Medicine, 32200 Isparta, Turkey
3Department of Pediatric Gastroenterology, Hepatology and Nutrition, Suleyman Demirel University, School of Medicine, 32200 Isparta, Turkey
4Department of Pathology, Suleyman Demirel University, School of Medicine, 32200 Isparta, Turkey

Received 9 December 2015; Accepted 23 February 2016

Academic Editor: John Broom

Copyright © 2016 Bunyamin Aydin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Diffuse amyloid goiter (AG) is an entity characterized by the deposition of amyloid in the thyroid gland. AG may be associated with either primary or secondary amyloidosis. Secondary amyloidosis is rarely caused by inflammatory bowel diseases. Secondary amyloidosis is relatively more common in the patients with Crohn’s disease, whereas it is highly rare in patients with ulcerative colitis. Diffuse amyloid goiter caused by ulcerative colitis is also a rare condition. In the presence of amyloid in the thyroid gland, medullary thyroid cancer should be kept in mind in the differential diagnosis. Imaging techniques and biochemical tests are not very helpful in the diagnosis of secondary amyloid goiter and the definitive diagnosis is established based on the histopathologic analysis and histochemical staining techniques. In this report, we present a 35-year-old male patient with diffuse amyloid goiter caused by secondary amyloidosis associated with ulcerative colitis.