Hashimoto’s Thyroiditis and Graves’ Disease in One Patient: The Extremes of Thyroid Dysfunction Associated with Interferon Treatment

<div>(a) Temporal pattern of thyroid function tests showing both hypothyroidism and subsequent T3-toxicosis, consistent with Graves’ Disease. (b) Thyroid antibodies showing persistently elevated anti-TPO and later development of thyrotoxicosis with positive TRAb titres. TSH,<i> thyroid stimulating hormone</i>; fT4,<i> free thyroxine</i>; fT3,<i> free triiodothyronine</i>; anti-TPO,<i> anti-thyroperoxidase antibody</i>; anti-TG,<i> anti-thyroglobulin antibody</i>; TRAb,<i> TSH receptor antibody</i>.</div>

Case Reports in Endocrinology

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Figure 1: Hashimoto’s Thyroiditis and Graves’ Disease in One Patient: The Extremes of Thyroid Dysfunction Associated with Interferon Treatment 