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Case Reports in Endocrinology
Volume 2017, Article ID 2652403, 3 pages
Case Report

Celiac Disease in Patients with Cystic Fibrosis-Related Bone Disease

1Division of Endocrinology, Boston Children’s Hospital, Boston, MA, USA
2Endocrine and Diabetes Units, Massachusetts General Hospital, Boston, MA, USA
3Pulmonary Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA

Correspondence should be addressed to Melissa S. Putman; gro.srentrap@namtupsm

Received 28 August 2017; Accepted 17 October 2017; Published 2 November 2017

Academic Editor: Suat Simsek

Copyright © 2017 Melissa S. Putman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Both cystic fibrosis (CF) and celiac disease can cause low bone mineral density (BMD) and fractures. Celiac disease may occur at a higher frequency in patients with CF than the general population, and symptoms of these conditions may overlap. We report on two patients presenting with CF-related bone disease in the past year who were subsequently found to have concurrent celiac disease. Because adherence to a gluten-free diet may improve BMD in patients with celiac disease, this could have important implications for treatment. Clinicians should consider screening for celiac disease in patients with CF who have low BMD, worsening BMD in the absence of other risk factors, and/or difficult to treat vitamin D deficiency.