Case Report

Humoral Hypercalcemia of Malignancy with a Parathyroid Hormone-Related Peptide-Secreting Intrahepatic Cholangiocarcinoma Accompanied by a Gastric Cancer

Table 2

Reported cases of cholangiocarcinoma secreting PTHrP who are alive for more than half a year.

NumberAuthorsAge Reported yearSexCa levelPTHrPTherapyPrognosis

(1)Davis et al. [17]541994Male16.45.2FUDR + 5-FUSurvival (for 6 months)
(2)Yamada et al. [4]432009Male14.45.0TAE + PTPE + GEM + S-1 + RadiationDied (after 14 months)
(3)Lim et al. [18]632013Male12.16.7CAP + CDDP + Radiation, second-line GEMDied (after almost 1 year)
(4)Our case742016Male14.826.6CDDP + GEMSurvival (after 1 year)

FUDR: floxuridine; 5-FU: 5-fluorouracil; GEM: gemcitabine; CAP: capecitabine; CDDP: cisplatin; TAE: transcatheter arterial embolization; PTPE: percutaneous transhepatic portal embolization; PTHrP reported by Lim et al. was measured 9 months after an ICC diagnosis; Ca level means corrected Ca.