Novel TMEM127 Variant Associated to Bilateral Phaeochromocytoma with an Uncommon Clinical Presentation

Figure 3

Bilateral phaeochromocytoma. Both right (a, c, d) and left (b, e, f) adrenal tumours were similar in the macroscopic and microscopic appearance. Microscopically they showed the typical nested pattern (c, e), moderate pleomorphism and occasional intracytoplasmic hyaline globules (arrows), but no mitotic activity. S100 sustentacular cells (d) and positivity for chromogranin A (f) were demonstrated. The Ki-67 was less than 2%.