Case Report

Untreated Giant Macroprolactinoma with Chronic Cerebrospinal Fluid Leakage: An Unusual Complication

Table 1

Summary of disease progression with treatment.

Treatment PeriodSerum Prolactin (mIU/L) 
(dilutional assay)
MRI Pituitary 
(tumor size)

Baseline250,6885.7 cm (AP) x 6.7 cm (W) x 7.5 cm (CC)
2 months37,487Essentially unchanged in size from baseline MRI
5 months19,118-
12 months14,7343.9 cm (AP) x 5.6 cm (W) x 6.7 cm (CC)

AP: anteroposterior, W: width, CC: craniocaudal.