Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) and Subsequent Central Diabetes Insipidus: A Rare Presentation of Pituitary Apoplexy

Figure 1

Plasma concentrations of sodium. Horizontal axis depicts time course from hospital admission (day 0) until 180 days’ follow-up. Vertical axis depicts plasma sodium concentrations (p-Na⁺). Hyponatremia was treated with intravenous hyperosmolar sodium infusion (3% NaCl at day 2) and fluid restriction (day 2 to day 5). The subsequent development of central diabetes insipidus (CDI) was treated with low dose desmopressin (initiated around day 60).