Age, sex (years, M/F) Race/ethnicity Acanthosis nigricans Triglyceride (mg/dL) HbA1c (%) [mmol/mol] C-peptide (ng/mL) Adiponectin (mcg/mL) Insulin antibody titer Insulin receptor antibody Maximum documented insulin requirement Associated rheumatologic/ malignancy diagnosis Our case 56, M Hispanic N 85 12.4 [112] 3 18 Elevated 2526 U/day Malek et al, Case B-30 [2 ] 20, F Black Y 42 11.9 [107] 54.4 Y 18000 U/day Mixed connective tissue disorder Malek et al, Case B-33 [2 ] 50, F Black 68 9 [75] 21.3 Y 1300 U/day Systemic lupus erythematosus Malek et al, Case B-34 [2 ] 62, M Black 36 9.2 [77] 12.5 Y 1250 U/day Systemic lupus erythematosus Malek et al, Case B-35 [2 ] 17, F Black Y 41 6.8 [51] 8.3 Y 0 U/day Malek et al, Case B-36 [2 ] 64, M Canadian 102 11.7 [104] 15.2 Y 1800 U/day Systemic lupus erythematosus Malek et al, Case B-37 [2 ] 58, F Black 92 10.2 [88] 24.8 Y 7000 U/day Malek et al, Case B-38 [2 ] 21, F Black 41 13.5 [124] 43.4 Y 750 U/day Kim et al, Case 1 [4 ] 63, M Black N 52 9.6 [81] 4.2 23 Borderline elevated Y 21000 U/day Kim et al, Case 2 [4 ] 61, F Jamaican Y 39 15.5 [146] 3.03 29 Y 11650 U/day Kim et al, Case 3 [4 ] 60, M Black N 103 10.8 [95] 1.75 16 Elevated N 1500 U/day Liminet et al. [5 ] 83, M N 11–12 [97–108] 3.0 Elevated N 100 U/hr Lymphocytic lymphoma Mizuhashi et al. [6 ] 62, M 10.4 [90] Elevated Pulmonary adenocarcinoma Takaya et al. [7 ] 66, M 11.9 [107] 5.24 Elevated N >150 U/day Greenfield et al. [8 ] 68, F White N 442 12.4 [112] 0.98 1.7 Elevated N >300 U/day Lahtela et al. [9 ] 27, M 12.6 [114] 0 Elevated 360 U/day Rhie et al, Case 1 [10 ] 71, M White Elevated N 440 U/day Waldenstrom macroglobulinemia Rhie et al, Case 2 [10 ] 69, M Elevated N 2050 U/day Multiple myeloma Segal et al. [11 ] 12, M White 12.5 [113] 0 Elevated 6000 U/day Willard et al. [12 ] 39, F Nigerian Y 72 12 [108] 8.56 9 Y >1000 U/day Systemic lupus erythematosus
