Case Report

Combination Therapy with Empagliflozin and Insulin Results in Successful Glycemic Control: A Case Report of Uncontrolled Diabetes Caused by Autoimmune Pancreatitis and Subsequent Steroid Treatment

Table 1

Postprandial laboratory results on patient’s first visit.

HematologyAuto-antibody tests
White blood cells7400/μLAntinuclear antibodies< 40
Red blood cells473×104/μL
Hemoglobin15.9 g/dLImmunoglobulin
Hematocrit44.9%Immunoglobulin A186 mg/dL
Platelets22.5×104/μLImmunoglobulin M90 mg/dL
Immunoglobulin G1104 mg/dL
Blood chemistryImmunoglobulin G4141 mg/dL
Albumin4.9 g/dL
T-bilirubin0.8 mg/dLTumor markers
Aspartate aminotransferase18 IU/LCEA5.7 ng/mL
Alanine aminotransferase20 IU/LCA19-91.2 U/mL
Lactate dehydrogenase162 IU/LSpan-1< 1.0 U/mL
Alkaline phosphatase448 IU/LDUPAN-257 U/mL
γ-Glutamyl transpeptidase47 IU/L
Pancreatic amylase13 IU/LGlycometabolism tests
Lipase18 IU/LPlasma glucose529 mg/dL
Trypsin111 ng/mLHbA1c13.1%
Elastase-193 IU/LGlycoalbumin43.2%
Cholinesterase290 IU/LC-peptide reactivity1.15 ng/mL
Creatinine kinase115 IU/LAnti-GAD antibodies< 5.0 U/mL
Uric acid4.3 mg/dL
Blood urea nitrogen11.5 mg/dLKetone body fractions
Creatinine0.64 mg/dLTotal ketone bodies895 μmol/L
eGFR95 ml/min/1.73m2Acetoacetate218 μmol/L
Sodium135 mEq/Lβ-Hydroxybutyrate677 μmol/L
Potassium4.1 mEq/L
Chloride98 mEq/LUrinalysis
Triglycerides195 mg/dLProtein( – )
HDL cholesterol65 mg/dLGlucose4+
LDL cholesterol115 mg/dLOccult blood( – )
C-reactive protein0.13 mg/dLKetones(+/–)