Hypertension Accompanied by Hyperaldosteronism, Hyperkalemia, and Hyperchloremic Acidosis: A Case Report and Literature Review

Table 1

Laboratory findings of the index patient.

Biochemical findings	Pre-HCTZ	Post-HCTZ	Reference values
Serum potassium	6.3	4.00	3.5–5.3 mmol/L
Serum sodium	142.8	138.9	137–147 mmol/L
Serum chlorine	114.7	96.4	99–110 mmol/L
Serum creatinine	60	N/A	37–110 μmol/L
eGFR	122	N/A	56–122 mL/min/1.73 m^2
Arterial blood pH value	7.286	7.400	7.35–7.45
	17.6	26.2	22–27 mmol/L
PRA renin activity	0.14	1.07	0.93–6.56 ng/mL/h
PRC aldosterone	31.00	15.2	9.8–27.6 ng/dl
Serum cortisol (8 AM)	300.2	N/A	147.3–609.3 nmol/L
Serum cortisol (4 PM)	162.0	N/A	34–340 nmol/L
Serum cortisol (midnight)	57.2	N/A	<50 nmol/L
24-h UFC	43.61	N/A	20.3–127.6 μg/24 h
ACTH	21.53	N/A	5.0–78 ng/L

Note. eGFR: estimated glomerular filtration rate; ACTH: adrenocorticotropin; UFC: urinary free cortisol; : serum bicarbonate; PRA: plasma renin activity; PRC: plasma aldosterone concentration; and HCTZ: hydrochlorothiazide.