Case Series

Clinical Characteristics and Treatment Outcomes in Endogenous Cushing’s Syndrome: A 15-Year Experience from Thailand

Table 3

Clinical characteristics of patients according to different subtypes of CS.

FeaturesCD (n = 45)Adrenal CS (n = 26)EAS (n = 11) value

Age (years)33 (28–43)40 (29–53)48 (45–64)0.003
Female (n, %)37 (82)22 (85)7 (64)0.308
Onset of symptoms (months)12 (7–24)12 (5–24)7 (3–12)0.427
Hypertension (n, %)29 (64)20 (77)7 (64)0.519
DM (n, %)14 (31)7 (27)3 (27)0.921
VTE (n, %)1 (2)1 (4)2 (18)0.085
Hypokalemia (n, %)9 (20)9 (35)5 (45)0.149
Morning cortisol (nmol/L)690 (497–828)690 (469–745)1269 (1131–1738)0.052
UFC (nmol/day)1593 (759–2616)378 (113–1673)3003 (2089–13794)0.013
Follow-up time (months)42 (18–75)32 (11–57)5 (2–65)0.174

Data were expressed in median (interquartile range). CS, Cushing’s syndrome; CD, Cushing’s disease; EAS, ectopic ACTH syndrome; DM, diabetes mellitus; VTE, venous thromboembolism; UFC, urinary free cortisol.