Severe Dental Disease as a Presenting Sign of Relapsed 6q24-Related Transient Neonatal Diabetes Mellitus

Table 1

Review of the literature of 6q24-related TNDM at relapse.

Reference	Age of relapse	HbA1c or fasting glucose level at relapse	Genetic variant	Treatment
Schimmel [10]	15 years	198 mg/dl	Uniparental paternal isodisomy of chromosome 6	Sulfonylurea
Yorifuji et al. [7]	12 years	7–7.5%	Paternal duplication at 6q24	Initially alpha-glucosidase inhibitor, then DPP4-inhibitor
Fu et al. [11]	14 years	8.2%, 204 mg/dl	Hypomethylation of the maternal allele	Insulin glargine and lifestyle modifications, transitioning to sulfonylurea