Type IV RTA in Chronic Adrenal Insufficiency and Concomitant Lisinopril Treatment

Figure 1

Effects of ACE-inhibitors on angiotensin conversion. ACE-inhibitors suppress the ACE enzyme action, thus blocking the conversion of angiotensin I to angiotensin II and its action on AT2 and AT1 receptors. The interaction between angiotensin II and AT1 receptors leads to aldosterone production.