Case Report
Late-Onset Isolated Corticotrope Deficiency in a Woman with Down Syndrome
Table 1
Blood biological and hormonal parameters.
| | | Values | Reference ranges |
| | Fasting glucose (mmol/L) | 4.95 | 3.84–5.44 | | Creatinine (μmol/L) | 61.8 | 61–106 | | Sodium (mmol/L) | 137 | 136–145 | | Potassium (mmol/L) | 4 | 3,5–5,1 | | Calcium (mg/L) | 87 | 85–105 | | Phosphorus (mg/L) | 29 | 23–47 | | White blood cells(mm3) | 7060 | 4000–10,000 | | Lymphocytes | 1360 | 1500–4000 | | Neutrophils | 5210 | 1500–7000 | | Hemoglobin (g/dL) | 13.1 | 12–16 | | TSH (mIU/L) | 1.97 | 0.35–4.95 | | FT4 (ng/dL) | 0.91 | 0.7–1.5 | | 8h cortisol (μg/dL) | 8.4 | 4–20 | | Pic cortisol (μg/dL) | 9.4 | ≥18 | | ACTH (pg/ml) | 21.4 | 10–48 | | Prolactin (ng/ml) | 20 | <25 | | FSH (IU/L) | 1.7 | 3.35–12.6 | | LH (IU/L) | 6.53 | 2.39–6.6 | | IGF1 (ng/ml) | 290 | 109–358 |
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