Case Report

Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

Table 1

Plasma parameters.

Blood sample: on admission

 WBC4.52 × 103/μLRBC4.41 × 106/μL
 Hb11.9g/dLPlt187 × 103/μL
 Creatinine6.61mg/dLeGFR5.4ml/min/1.73 m2
 Na144mEq/LK3.7mEq/L
 PRA≦0.2ng/mL/hrPAC514.9pg/mL
 ACTH25pg/mLCortisol14.5μg/dL
 DHEA-S25μg/dLEstradiol<14.0ng/mL
 Testosterone0.24ng/mLHbA1c5.6%

Urine sample
 U-adrenaline1.08μg/dayU-VMA2.16mg/day
 U-noradrenaline55.26μg/dayU-metanephrine0.036mg/day
 U-dopamine100.8μg/dayU-normetanephrine0.126mg/day
 U-cortisolBelow the detection limit

Diurnal profile of ACTH and cortisol
 Time6 : 0023 : 00
 ACTH (pg/mL)237
 Cortisol (μg/dL)16.46.9

Low-dose dexamethasone suppression test
After 1 mg
 ACTH (pg/mL)2
 Cortisol (μg/dL)4.5

Blood sample: one month after surgery
 K4.4mEq/LeGFR5.1ml/min/1.73 m2
 PRA≦0.2ng/mL/hrPAC533.6pg/mL
 ACTH31pg/mLCortisol13.5μg/dL
 DHEA-S3.8μg/dL