Case Report

Bilateral Leydig Cell Hyperplasia: A Rare Cause of Postmenopausal Hirsutism

Table 1

Relevant hormonal evaluation of the patient.

InvestigationValueReference range

Total testosterone123 ng/dL14–76 (adult female)
FSH31.92 IU/L23–116.3 (postmenopausal)
LH26.33 IU/L15.9–54 (postmenopausal)
Prolactin5.8 mU/L48–430 (postmenopausal)
9.00 am cortisol (ODST)24 nmol/L<50
DHEAS1 μmol/L0.8–4.9
17-OHP5.8 nmol/L<6 excludes 21OHD
SHBG53.3 mmol/L13.5–71.4

FSH: follicle-stimulating hormone; LH: luteinizing hormone; ODST: overnight dexamethasone suppression test; DHEAS: dehydroepiandrosterone sulphate; 17-OHP: 17-hydroxyprogesterone; SHBG: sex hormone binding globulin, 21OHD: 21–hydroxylase deficiency.