Case Report

Giant Pheochromocytoma Diagnosis Confounded by Amphetamine Use

Table 1

Summary of patients’ laboratory evaluation data during initial workup, after 1 week of drug washout period, and following surgical removal of her tumor.

InitialDrug washoutPostoperation day 3 (follow-up)Normal reference range

Plasma metanephrine (nmol/L)158<0.2<0.50 nmol/L
Plasma normetanephrine (nmol/L)26130.7<0.9 nmol/L
Urine metanephrine (mcg/24 hr)188508477390149–535 mcg/24 hr
Urine normetanephrine (mcg/24 hr)1176075841992111–419 mcg/24 hr
Urine total metanephrine (mcg/24 hr)303101605123823–180 mcg/24 hr
24 hr urine cortisol (mcg/24 hr)1803.5–45 mcg/24 hr
Random serum cortisol (μg/dL)10435222–14 μg/dL