Severe Hypercalcemia Caused by Calcium-Alkali Syndrome after 15 Years of Postoperative Hypoparathyroidism in a Patient with Undiagnosed Hyperaldosteronism
Table 1
Laboratory tests presented chronologically.
Reference range
−14 years
−13 years
−12 years
−11 years
−10 years
−8 years
−5 years
−1 years
D0
D7
D21
D35
D60
D90
D125
D165
D175
Hemoglobin (g/dL)
13.2–18.0
16.5
15.8
15.9
16
14.7
10.2
8.9
10
11.1
11.6
11.8
Hematocrit (%)
39.1–50
48
46.2
45.5
46.1
42
30.1
26.9
29.9
33.2
35.5
35.8
MCV (fL)
80–99
85
85.3
85
85.8
84.2
88.5
89.4
89.9
87.1
87
86.9
Leucocytes (μL)
3700–9500
6500
5670
6010
6310
6000
8740
8120
5340
6570
6230
7570
Platelets (μL)
140000–400000
220000
211000
223000
294000
299000
244000
240000
223000
240000
Creatinine (mg/dL)
0.66–1.25
0.94
1.01
1.12
1.48
7.31
5.9
4.3
3.8
3.6
3
3
2.3
eGFR (ml/min/1.73 m2)
>60
89.7
77.9
68
49
7.6
9.8
15
16.3
17.3
21.4
21.4
29
Potassium (mmol/L)
3.5–5.1
4.1
3.7
4.2
4.2
4.4
3.9
3.7
4.4
4.2
Sodium (mmol/L)
137–145
135
140
142
140
141
142
139
Calcium (mg/dL)
8.4–10.2
7.9
7.7
8.4
8.3
8.5
9.4
9
17.1
10.7
9
9.6
9.6
9.3
8.3
7
8.1
Albumin (g/dL)
3.5–5.0
4.43
4.4
4
4.3
4.3
Bicarbonate (mmol/L)
22–30
33
28
25
27
28
26
Phosphate (mg/dL)
2.5–4.5
5.8
5.18
4.8
4.73
4
3.9
3.8
4.6
3.8
4.7
5
4.8
4.7
4.3
5.6
4.6
Glycemia (mg/dL)
70–100
89
93
94
95
94
97
95
96
78
TSH (mUI/L)
0.51–4.30
1.99
0.03
<0.01
<0.05
0.72
1.7
1.6
0.16
2.35
2.01
Free T4 (ng/dL)
0.93–1.7
1.28
1.5
2.1
1.6
1.5
1.4
1.4
1.3
1.19
1.18
Thyroglobulin (ng/ml)
1.1–55
0.39
<0.2
0.2
PTH (pg/mL)
4.0–65.0
<2.5
6
9
2.9
5.3
5.8
9.9
11.9
11
25-OH-VitD (ng/mL)
20–60
39
36.6
34
48.6
1.25-OH-VitD (pg/mL)
19.9–79.3
10
<15
Aldosterone (ng/dL)
2.5–39.2
64.1
76.9
Renin (ng/mL/H)
0.04–4.95
1
0.8
Urinary calcium (mg/24 h)
100–300
269
364
423
156
229
79
D: day; eGFR: estimated glomerular filtration rate; MCV: mean corpuscular volume; T4: thyroxine; PTH: parathyroid hormone; TSH: thyroid-stimulating hormone; VitD: vitamin D. Time data: D0: hypercalcemia diagnosis; (-): time before D0.
