Epistaxis as a Common Presenting Symptom of Glanzmann’s Thrombasthenia, a Rare Qualitative Platelet Disorder: Illustrative Case Examples

Table 1

Types of congenital platelet function disorders.

Type of platelet function defect	Diagnoses	Protein or functional deficiency
Cytoskeletal assembly	Wiskott-Aldrich syndrome	Wiskott-Aldrich syndrome protein
Granule storage or release	Storage pool deficiencies	Granule platelet content
Platelet adhesion	Von Willebrand disease	VWF
	Bernard-Soulier syndrome	GPIb
Platelet aggregation	Glanzmann’s thrombasthenia	GPIIb/IIIa
	Congenital hypofibrinogenemia	Fibrinogen
Platelet-agonist interactions	Agonist receptor deficiencies	ADP or thromboxane A2
Platelet coagulant-protein interactions	Scott syndrome	Platelet membrane phospholipid signaling

ADP, adenosine diphosphate; GP, glycoprotein; VWF, Von Willebrand factor.