Case Report
Consequences of Misdiagnosed and Mismanaged Hereditary Angioedema Laryngeal Attacks: An Overview of Cases from the Romanian Registry
Table 1
History and clinical data of 4 patients with hereditary angioedema (HAE) who died from laryngeal edema and asphyxiation.
| Pt | Gender | Age (years) | HAE attacks | | Family history | | Treatment received | | At onset of symptoms | At HAE diagnosis | At death | Frequency of previous abdominal and/or peripheral attacks | No. of previous laryngeal attacks | Unnecessary abdominal surgeries before diagnosis? | No. of known relatives with HAE | Relatives experiencing laryngeal edema? | No. of deaths in family resulting from suspected laryngeal edema? | Interval between onset of laryngeal edema and asphyxiation | Home | Emergency services / Hospital | Emergency procedures administered |
| 1 | Female | 20 | 50 | 52 | Weekly | >100 | 3 | 6 | Yes | - | 6 h | - | - | - |
| 2 | Male | 3 | 7 | 11 | Monthly | 3 | 1 | 4 | Yes | 2 | 3 h | - | Corticosteroids and epinephrine | - |
| 3 | Male | 8 | 57 | 59 | Yearly | 10 | - | 3 | Yes | - | 20 min | - | - | - |
| 4 | Male | 22 | Not previously diagnosed | 42 | Twice/ month | 0 | - | 5 | Yes | 5 | 11 h | Corticosteroids | Epinephrine | Attempted (self-) tracheotomy |
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