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| Reference | Age, sex | Dose, formula | Presentation | Drug concentration | Management | Outcome |
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| Present case | 3-year-old male | Up to 27.6 mg/kg in ODT tablets | Acute: 1 seizure <1 minute in duration within 1 hour with myoclonic activity, dysconjugate gaze, coma | 23.2 mcg/mL (3-4-hour level) & 18.5 mcg/mL (24-hour level) | Lorazepam, intubation | Discharged well after 72 hours |
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| Grosso (2016) | 3.2-year-old male | 1600 mg total (wt not given)
200 mg tablets | Acute: tonic-clonic status epilepticus upon presentation. After 30 min postictal pattern | 28.4 mg/L after 10 hours of fluids | Rectal diazepam x 2, IVP
midazolam, then cont infusion | Discharged at approx 72 hrs. Hyperphagia still present at discharge |
|
| Moore (2013) | 1-year-old female | Unknown quantity | Acute: initially agitated and crying with intermittent myoclonus of her extremities | 18 mg/L at 8 h and
11.8 mg/L at 19 h | Lorazepam | Discharged well after 19 hours |
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| Close (2010) | 2-year-old male | Up to 43 mg/kg tablet | Acute: 2 seizures of 5-second duration within 3 hours with ataxia, drowsiness, nystagmus, hyperreflexia vomiting | Not available | Diazepam | Discharged well after 12 hours |
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| Thundiyil (2007) | 19-month-old male | Unknown amount of a chewable tablet | Acute: 2 seizures of <10-second duration in 1 hour with irritability, vomiting, sinus tachycardia | 20.3 mg/L (1-hour level) | Activated charcoal | Discharged well after 24 hours |
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| Willis (2007) | 12-day-old male | Not available | Acute: repeated poisoning (including in the hospital); 2 seizures (9 days apart), with arm movements, irritability, poor interaction, poor feeding | 35 mg/L (2 days after the second seizure) | Lorazepam, phenytoin, paraldehyde | 19-day admission with seizures at days 4 and 13, discharged well to child protection |
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| Lofton (2004) | 3-year-old female | Not available | Acute: multiple seizures with vomiting | Not available | Not available | Not available |
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| Briassoulis (1998) | 2-year-old male | 62 mg/kg tablet | Acute: 2 seizures (15- and 5-minute duration) within 90 minutes with muscle weakness and incoordination, ataxia, tremor, hypertonia | 3.8 mg/L (2-hour level) | Midazolam, gastric lavage, activated charcoal | Discharged well after 48 hours |
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