Case Report
Chromosome Deletion of 14q32.33 Detected by Array Comparative Genomic Hybridization in a Patient with Features of Dubowitz Syndrome
Table 1
Comparison between the clinical features of Dubowitz syndrome, 14q.32 deletion syndrome, and the patient.
| Feature | Dubowitz syndrome | 14q.32 deletion syndrome | Patient |
| IUGR | + | + | + | Low birth weight | + | + | + | Microcephaly | + | + | + | Poor feeding | + | + | + | Postnatal growth retardation | + | + | + | High forehead | − | + | + | Ptosis | + | + | + | Blepharophimosis | + | + | + | Telecanthus | + | + | + | Epicanthal folds | + | + | + | Hypertelorism | − | + | − | Asymmetry in eye features | + | Not reported | + | Wide nasal bridge | + | + | + | Round tipped nose | + | + | + | Dysplastic low-set ears | + | + | + | Micrognathia | + | + | + | Palate anomalies | + | +High arched | − | Sparse, light-colored hair | + | Not reported | − | Lateral forehead hypertrichosis | − | + | − | Hypotonia | + | + | + | Mild or moderate developmental delay in 50% | + | + | + | Hyperactivity (in some) | + | Not reported | − | Eczema (~50% cases) | + | Not reported | − | High-pitched, hoarse voice | + | Not reported | + | Syndactyly 2nd and 3rd toes (in some) | + | − | − | Single palmar crease | − | + | − | Clinodactyly | − | + | − | Cryptorchidism, inguinal hernias, and hypospadias in some boys | + | − | −Patient is female |
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