MOMO Syndrome with Holoprosencephaly and Cryptorchidism: Expanding the Spectrum of the New Obesity Syndrome

Table 1

Comparison of the cases reported in literature [1].

Cases reported	Moretti-Ferreira et al., [3]	Moretti-Ferreira et al., [3]	Zannoli et al., [4]	Wallerstein and Sugalski, [1]	Present case 2011
Sex	M	F	F	M	M
Macrosomia	+	+	−	+	+
Obesity	+	+	+	+	+
Macrocephaly	+	+	+	+	+
Ocular abnormalities	+	+	+	+	+
Downslanting palpebral fissures	+	+	+	+	+
Hypertelorism	+	+	+	+	+
Broad nasal root	+	+	+	+	+
Mental deficiency	+	+	+	+	+
High broad forehead	+	+	+	+	+
Delayed bone maturation	+	+	+	+	+
Additional features			Recurvation of the femur,; Short stature	Sparse eyebrows,; Clavicular pseudoarthrosis	Cryptorchidism,; Holoprosencephaly,; Hepato-splenomegaly
Thyroid studies	Normal	Normal	Normal	Normal	Normal
Karyotype					Normal