Case Reports in Genetics / 2013 / Article / Tab 1

Case Report

MURCS Association with Partial Duplication of the Distal Long Chromosome 5 and Unilateral Ovarian Agenesis

Table 1

Action of genes in region 5q35.1. Based on OMIM 20/11/2012.

Genes in region 5q35.1Action of genes

TLX3 T-cell leukemia is caused by the defect of the gene
RANBP17 Acute lymphoblastic leukemia is caused by the mutation of the gene
NPM1 and ALK Fusion of these 2 genes can cause acute medullary leukemia
FGF18 Participates in oncogenesis; it also influences the differentiation of osteoblasts and chondrocytes and the development of cartilage forming from mesenchymal lung tissue

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