MURCS Association with Partial Duplication of the Distal Long Chromosome 5 and Unilateral Ovarian Agenesis
Table 1
Action of genes in region 5q35.1. Based on OMIM 20/11/2012.
Genes in region 5q35.1
Action of genes
TLX3
T-cell leukemia is caused by the defect of the gene
RANBP17
Acute lymphoblastic leukemia is caused by the mutation of the gene
NPM1 and ALK
Fusion of these 2 genes can cause acute medullary leukemia
FGF18
Participates in oncogenesis; it also influences the differentiation of osteoblasts and chondrocytes and the development of cartilage forming from mesenchymal lung tissue