Warfarin Dosing in a Patient with CYP2C9*3*3 and VKORC1-1639 AA Genotypes

Table 1

Case reports of warfarin-dosing in patients with CYP2C9*3*3 and VKORC1-1639 AA genotypes.

Age (yrs)	Weight (kg)	Gender	Ethnicity	Indication	Target INR	Drug Interaction(s)	Therapeutic warfarin dose (mg/d)	Reference
69	79.8	Female	Japanese	AFib	1.5–20	NR	0.5	[8]
71	82	Male	White	AFib	2.0–3.0	Amiodarone	0.9	[11]
58	70	Male	Japanese	AFib	NR	Propafenone	0.25–0.75	[12]
68	70	Female	Chinese	AFib	2.0–3.0	NR	0.63	[13]
50	88	Male	Chinese	AFib	2.0–3.0	NR	1.25	[13]
74	54	Female	White	AFib	2.0–3.0	Amiodarone/; Atorvastatin	0.5	Present case

AFib: atrial fibrillation; NR: none reported.