Case Report
A Case of False Negative NIPT for Down Syndrome-Lessons Learned
Table 1
Commercially advertised NIPT statistics [
1,
6,
16–
20].
| | | Sequenom
MaterniT21 PLUS | Verinata
Verifi | Ariosa
Harmony | Natera
Panorama |
| | Sensitivity | 98.6%–99%
(209/212) | >99%
(90/90) | 100%
(81/81) | >99%
(25/25) | | Specificity | 99.8%
(1468/1471) | 99.8%
(409/410) | 99.97%
(2887/2888) | >99%
(242/242) | | False positive | 0.2%
(3/1471) | 0.2%
(1/410) | 0.03%
(1/2888) | 0 | | No call rate | 3.4% | 5.8% | 4.7–5.7% | 5.4% |
|
|
