Case Reports in Genetics / 2018 / Article / Tab 1

Case Report

Chromosomal Abnormalities in Syndromic Orofacial Clefts: Report of Three Children

Table 1

Molecular karyotype with chromosomal base pair location, size, number of genes, and critical regions in the case series.

ProbandMolecular karyotypeBase pair location (mb)Size (mb)Number of genesCritical regions

1.arr11q23.3q25 x 3;116.7 – 134.918.2180Duplicated material
arr22q11.1q11.21 x 316.1 – 20.74.665
2.arr4q27q35.2 x 3;121.7 – 190.9692264q33q34 – Developmental disability
and craniofacial dysmorphism
4q26q27 – Cardiac
4q25q31.3 – Urogenital
arr21q22.2q22.3 x 140.8 – 48.17.3105
3.arr12p13.33p13.32 x 3;0.2 – 4.54.33318q22.2q23 – Cleft lip palate
arr18q22.3q23 x 170.9 – 78.07.128