Identification and Mapping of a 2,009-bp DNA Deletion in SERPING1 of a Hereditary Angioedema Patient

Figure 2

Genomic DNA sequence electropherograms of the patient and her mother, in comparison with the reference sequence. The deletion is 2,009 bps in size and encompasses exons 5 and 6. The red arrows locate the 3′ end breakpoint, whereas the red frame illustrates a part of the deleted sequence. The deletion boundaries are noted on the patient strand, as indicated by the nucleotide positions.