Towards New Approaches to Evaluate Dynamic Mosaicism in Ring Chromosome 13 Syndrome

Figure 2

WCP13 probe (green): (a) patient 2, normal 13 and monocentric ring; (b) patient 1, two monocentric rings and normal 13; (c) patient 3, normal 13 and marker with positive hybridization (arrow); (d) patient 2, normal 13 and dicentric ring; (e) patient 1, single normal 13 in a monosomic cell; (f) patient 1, on the left, metaphase with monocentric ring and normal 13, near an interphasic nucleus bordered by a micronuclei, the latter also showing positive hybridization.

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