Case Report
A Specific Diplotype H1j/H2 of the MAPT Gene Could Be Responsible for Parkinson’s Disease with Dementia
Table 2
Comparison of frequencies of the MAPT diplotypes between PD patients and controls.
| | Subjects (N) | Diplotype, n (%) | OR | value | | H1/H1 | H1/H2 or H2/H2 | H1j/H2 |
| | All PD (186) | 152 (81,7) | 34 (18,3) | 3 (1,61) | | | | Familial PD (48) | 41 (85,4) | 7 (14,6) | 0 (0,00) | | | | Sporadic PD (138) | 111 (80,4) | 27 (19,6) | 3 (2,17) | | | | Idiopathic sporadic PD (80) | 63 (78,7) | 14 (17,2) | 3 (3,75) | 3,55 | 0,277 | | Control subjects (92) | 71 (77,2) | 21 (22,8) | 1 (1,08) | | |
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