Case Reports in Genetics / 2021 / Article / Tab 1

Case Report

Genomic Characterization of Radiation-Induced Intracranial Undifferentiated Pleomorphic Sarcoma

Table 1

Results from the targeted cancer gene panel of the index patient.

GeneGene full nameConsequenceVariant(protein)Variant (coding DNA)Predicted effectsAllelic fractionChromosomeCopy number

KITv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologMissenseV603Dc.1808T > ADeleterious (SIFT), probably damaging (PolyPhen)0.734q127
TP53Tumor protein p53MissenseY220Cc.659A > GDeleterious (SIFT), probably damaging (PolyPhen)0.6217p131
PDGFRAPlatelet-derived growth factor receptor, alpha polypeptideN/AN/AN/AN/AN/A4q127