Genomic Characterization of Radiation-Induced Intracranial Undifferentiated Pleomorphic Sarcoma

Table 1

Results from the targeted cancer gene panel of the index patient.

Gene	Gene full name	Consequence	Variant(protein)	Variant (coding DNA)	Predicted effects	Allelic fraction	Chromosome	Copy number
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	Missense	V603D	c.1808T > A	Deleterious (SIFT), probably damaging (PolyPhen)	0.73	4q12	7
TP53	Tumor protein p53	Missense	Y220C	c.659A > G	Deleterious (SIFT), probably damaging (PolyPhen)	0.62	17p13	1
PDGFRA	Platelet-derived growth factor receptor, alpha polypeptide	N/A	N/A	N/A	N/A	N/A	4q12	7