The Benefits of Early versus Late Therapeutic Intervention in Fabry Disease

Figure 3

Medical history and occurrence of events over time in two female patients treated at different stages of FD. ^aAT1001-011 (NCT00925301), ^bAT1001-041 (NCT01458119), and ^cAT1001-042 (NCT02194985). AV, atrioventricular; ECG, echocardiogram; eGFR, estimated glomerular filtration rate, normal: >90 and >60 for omen >50 years¹⁵; FD, Fabry disease; GI, gastrointestinal; IBD, irritable bowel syndrome; LVEF, left ventricular ejection fraction; LVH, left ventricular hypertrophy; OLE, open-label extension.