Case Report

Rare Cause of Stricture Esophagus—Sarcoma: A Case Report and Review of the literature

Table 1

Morphological variants of esophageal sarcoma.

TypeImmunohistochemistryIncidence (among esophageal cancer)SurvivalReference

1. CarcinosarcomaPositive for cytokeratin, vimentin, smooth muscle actin, and p53 [10]Approximately 6%DFS* of 45 monthsNakagawa et al., [11]
2. LeiomyosarcomaStrongly positive for SMA, negative for cytokeratin [12]0.5%DFS* of 14 months, survival of 20 monthsAdad et al., [12]
3. LiposarcomaPositive only for S100Very rare; nearly 13 to 15 reported casesNot mentionedGarcia et al., [13]
4. Synovial sarcomaBiphasic morphologic findings positive for vimentin, epithelial (EMA, CK7, AE1/3), bcl-2, and neuroectodermal (CD56, CD57, CD99)X;18 translocation on FISH [14]Very rare; nearly 10 cases reportedNot knownButori et al., [15]
5. MyxofibrosarcomaPositive for CD34, smooth muscle actin, negative for S-100, C-kit, and desmin [4]Very rare; 1 to 2 cases reportedNot knownSong and Miller, [4]
6. Ewing’s sarcomaMIC2/CD99 positiveVery rare; 1 to 2 cases reportedNot knownMaesawa et al., [5]
7.Granulocytic sarcomaSubepithelial dense deposits of myeloid cells histologicallyVery rareNot mentionedIbrarullah et al., [6]
8.Histiocytic sarcomaPositive for CD68 and negative for CD1a and CD35, negative for Ki-1 antigen and T-cell and B-cell lineage markers [7]Very rare1 monthAkishima et al., [7]
9. SchwannomaPositive for S100 and vimentin; negative for CD117Very rareNot knownSanchez et al., [8]
10. RhabdomyosarcomaIntracytoplasmic cross striations histologicallyVery rare;15 reported casesNot known Batoroev and Nguyen, [9]
11. Epithelioid sarcomaPositive for both epithelial and mesenchymal markers, such as cytokeratin, epithelial membrane antigen (EMA), vimentin and CD34Very rareNot mentionedMaggiani et al., [16]

*disease-free survival.