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Case Reports in Gastrointestinal Medicine
Volume 2012, Article ID 287012, 3 pages
http://dx.doi.org/10.1155/2012/287012
Case Report

Primary Leiomyosarcoma of Gallbladder: A Rare Diagnosis

1Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
2Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
3Department of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India

Received 21 April 2012; Accepted 28 June 2012

Academic Editors: N. Courcoutsakis, R. Goll, and V. Lorenzo-Zúñiga

Copyright © 2012 Ajay Savlania et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Leiomyosarcoma of the gallbladder is a rare entity, constituting about 1.4 per 1000 gallbladder malignancies. Literature review shows female preponderance in sixth decade of life, due to unknown reasons. We report one such rare case of a 50-year-old female admitted with pain in right upper abdomen. On examination, mass was felt in right hypochondrium. The ultrasound abdomen showed mass with loss of interface with liver and cholelithiasis. CECT abdomen showed polypoidal gallbladder malignancy with ill-defined interface with liver. She was operated upon with diagnosis of carcinoma gallbladder; extended cholecystectomy was done. Histopathological examination revealed spindle-cell proliferation and possibility of malignant tumor of mesenchymal origin was kept. This was later confirmed on immunohistochemistry.