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Case Reports in Gastrointestinal Medicine
Volume 2013 (2013), Article ID 676327, 2 pages
Case Report

Celiac Disease Presenting as Fever of Unknown Origin

1Department of Pediatrics, AE405-840 Sherbrook Street, Winnipeg, MB, Canada R3A 1S1
2Section of Pediatric Gastroenterology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada

Received 14 March 2013; Accepted 17 June 2013

Academic Editors: G. Bassotti, Y. Moriwaki, and Ö. Yönem

Copyright © 2013 Megan J. Cooney and Wael El-Matary. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Celiac disease (CD) is a common autoimmune enteropathy that occurs, in affected individuals, with exposure to gluten in the diet and improves with removal of dietary gluten. Although CD is readily considered in patients with classical presentations of the disease, atypical manifestations may be the only presenting symptoms. We present a case of CD in a 16-year-old female presenting as fever of unknown origin, which has not been reported previously. The postulated mechanism for fever in CD and the importance of clinicians having a low threshold for considering CD in the differential diagnosis of fever of unknown origin and other enigmatic clinical presentations is discussed.