Case Report

Marked Direct Hyperbilirubinemia due to Ceftriaxone in an Adult with Sickle Cell Disease

Table 1

Serologic evaluation of elevated direct hyperbilirubinemia.

Serological evaluation of direct hyperbilirubinemiaPatient’s valueNormal value

Serum copper level24372–166 mcg/dL
Ceruloplasmin5915–30 mg/dL
Ferritin1,85030–400 ng/mL
Iron8159–159 mcg/dL
Total Iron Binding Capacity (TIBC)207228–428 mcg/dL
Unsaturated Iron Binding Capacity (UIBC)126112–346 mcg/dL
Iron saturation3920–55%
Folate9.63.1–17.5 ng/mL
Vitamin B12697211–946 pg/mL
Serum zinc13060–130 mcg/dL
Hepatitis A totalNegativeNegative
Hepatitis B core antibody IgMNegativeNegative
Hepatitis B surface antibodyNegative0.0–9.9 Iunits/mL
Hepatitis B surface antigenNegativeNegative
Hepatitis C antibodyNegativeNegative
Total IgG1480700–1600 mg/dL
Total IgA37670–400 mg/dL
Total IgM1940–230 mg/dL
Antinuclear Antibody (ANA)NegativeNegative
Mitochondrial antibodyNondetectedNondetected
Smooth muscle antibodyNondetectedNondetected