Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding

Figure 2

(a) (H&E, 20×) Poorly differentiated hepatocellular carcinoma composed of large epithelial cells with abundant pink cytoplasm and central atypical nuclei. (b) (H&E, 20×) Glypican-3 immunostain positive (brown chromogen). (c) (H&E, 40×) Polyclonal carcinoembryonic antigen immunostain highlights a positive canalicular pattern (arrowheads). (d) (H&E, 40×) Hepatocyte paraffin-1 immunostain (brown chromogen).

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