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Case Reports in Gastrointestinal Medicine
Volume 2017, Article ID 4014565, 3 pages
Case Report

Plexiform Fibromyxoma: A Rare Gastric Tumor

1Aga Khan University, Dar es Salaam, Tanzania
2Texas A&M University, College Station, TX, USA

Correspondence should be addressed to Casmir Wambura; ude.uka@arubmaw.rimsac

Received 27 September 2017; Accepted 1 November 2017; Published 26 November 2017

Academic Editor: Yoshihiro Moriwaki

Copyright © 2017 Casmir Wambura and Salim Surani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Plexiform fibromyxoma is a rare and distinctive benign mesenchymal neoplasm that occurs in the gastric antrum. This tumor has a potential for misdiagnosis as gastrointestinal stromal tumor (GIST). It causes mucosa and vascular ulcerations without advancement of the tumor. Cytological bland spindle cells within a variably myxoid stroma characterize the histology of the tumor. We report the case of a 41-year-old African Tanzanian lady who presented with melena and recurrent anemia. Endoscopy and imaging studies revealed antral mass with initial suspicion of a GIST. However, immunohistochemically it turned to be a plexiform fibromyxoma. Follow-up evaluation 12 months after surgery revealed no evidence of recurrence or metastasis. This is a very uncommon tumor, which, to our knowledge, has been reported only once in Africa. The clinicians need to be aware of this rare occurrence to avoid misdiagnosis as GIST tumor.