|
Author | Date | Sex | Age | UC Activity | IBD Treatment | Neurological symptoms | Site of cerebral injury/neurological findings | Risk Factor | Thrombophilia screening | Anticoagulation/antiplatelet treatment | Follow-up/outcome |
|
Calabro et al. [10] | 2011 | F | 49 | No | | Right hemiparesis, aphasia, altered conscious | Left frontotemporal infarct, lesion in the left mesencephalic area, left ICA stenosis | Hypercholesterolemia, elevated Lpa | | LMWH (nadroparine 0.6 ml/d), aspirin (300 mg/d) / clopidogrel (75 mg/d) | Improved |
Casella et al. [11] | 2013 | M | 25 | Yes | | Left hemiparesis, confusion, sensitive impairment, bladder incontinence | Right MCA infarct | Anemia | | Local thrombolysis/ LMWH and aspirin (100 mg/d) | Complete recovery |
Chetri et al. [12] | 2002 | M | 42 | Yes | Steroids, 5-ASA | Left hemiplegia | Right MCA infarct and right CCA occlusion | Anemia | | | Improved |
Fukuhara et al. [13] | 1993 | M | 18 | No | Steroids | Left hemiparesis | Right paramedian branch of the basilar artery infarct, Ventromedial pons | Anemia | | | Complete recovery |
Hilton-Jones et al. [14] | 1985 | M | 20 | No | | | Basal ganglia infarct | Anemia, abnormal platelet aggregation | | | Recurrent thrombotic episodes, death |
Houissa et al. [4] | 2011 | M | 24 | Yes | Steroids | Left hemiplegia | Left MCA infarct | | Neg | LMWH | Complete recovery |
Houissa et al. [4] | 2011 | F | 25 | Yes | 5-ASA | Left hemiparesis | Tenticular & right thalamic infarcts | Thrombocytosis | Neg | LMWH | Partial recovery (Residual right hemiparesis) |
Jorens et al. [15] | 1990 | M | 31 | Yes | 5-ASA | Right hemiparesis, nonconfluent aphasia | Recent ischemic lesion in left internal capsule and old ischemic lesion in left basal ganglia | Anemia, thrombocytosis, pro-C, pro-S and prothrombin deficiency, history of TIA | | | Partial recovery |
Jorens et al. [16] | 1991 | M | 32 | Yes | | Left hemiparesis, stupor, hemiataxia | Temporoparietal cerebrovascular ischemic lesion | | | | Complete recovery |
Joshi et al. [17] | 2008 | M | 55 | Yes | Steroids, 5-ASA | Left hemiparesis | Right parietal lobe infarction | Thrombocytosis | Neg | LMWH | Partial recovery |
Joshi et al. [17] | 2008 | M | 24 | Yes | Steroids, 5-ASA | Headache, altered conscious, global aphasia | Left MCA infarct | Thrombocytosis | Neg | | Complete recovery, subsequent epilepsy |
Keene et al. [18] | 2001 | F | 13 | Yes | Steroids, subtotal colectomy | Seizure | Multiple bilateral cerebellar and corona radiata infarcts | Anemia | | | Complete recovery |
Kelly et al. [19] | 2014 | M | 38 | No | Steroids, AZA, infliximab | bilateral lower limb claudication, acute confusion with associated ataxia and diplopia | right medial temporal lobe extending posterior to the occipital lobe | | Neg | Warfarin | Controlled |
Lloyd-Still and To masi [20] | 1989 | M | 5 | Yes | Steroids, 5-ASA | Right hemiparesis, seizure | Left MCA arteritis | Anemia | | | Partial recovery, epilepsy developed 10 years later |
Mayeux and Fahn [21] | 1978 | M | 17 | Yes | Steroids | | Right posterior frontal area infarction | | | | Slowly improved |
Nogami et al. [22] | 2007 | F | 26 | Yes | Steroids | Left hemiparesis | Right MCA Infarct and right CCA occlusion | Severe anemia | | Heparin (15.000 U/d) | Massive GI bleeding, no improvement |
Paradis et al. [23] | 1985 | F | 12 | Yes | | Right hemiparesis, seizure | Left major cerebral vessels occlusion | Anemia, thrombocytosis | | | Complete recovery |
Patterson et al. [24] | 1971 | M | 11 | Yes | | | Cerebral emboli | | | | Colectomy |
Richard et al. [25] | 2014 | F | 42 | Yes | Steroids, AZA | Sudden right hemiplegia | Right MCA | Slight hyperhomocysteinemia | | LMWH, Enoxaparin sodium, Aspirin | |
Salloum et al. (our case) | 2016 | F | 15 | No | Steroids, 5-ASA, AZA | Left hemiparesis, 7th CN palsy | M2-M3 segments of the Right MCA | Pancytopenia | Neg | Aspirin 162mg | Colectomy, complete recovery |
Schneiderman et al. [26] | 1979 | M | 34 | Yes | | Right hemiplegia, nonfluent aphasia | Left ICA thrombosis | Thrombocytosis | | Thrombectomy, heparin/warfarin | |
Schneiderman et al. [26] | 1979 | F | 12 | Yes | Steroids, 5-ASA | Hemianopia, headache, seizures | Distal basilar artery defect extending to the left PCA | Elevated fVIII | | | Death |
Tomomasa et al. [27] | 1993 | F | 1 | Yes | Steroids, 5-ASA | Right hemiplegia, altered conscious, seizures | Left anterior & MCA infarct/ right MCA infarct | Thrombocytosis, bacterial endocarditis | | | No improvement |
Yassinger et al. [28] | 1976 | F | 15 | Yes | Steroids | | Right frontal lobe infarction | | | | Recovered |
|