Somatostatinoma Presented as Double-Duct Sign

Figure 3

Histopathology images H&E [4x (a) and 0x (b)] reveal ampullary neuroendocrine tumor infiltrating the mucosa, submucosa, and muscularis propria with angiolymphatic invasion. Immunohistochemical stain images are positive for somatostatin [4x (c) and 10x (d)], and synaptophysin [2x (e) and 4x (f)].

(a)

(b)

(c)

(d)

(e)

(f)