Case Report
Benign Recurrent Intrahepatic Cholestasis (BRIC): An African Case Report
| Investigation | Reference range | 26/06/16 attack 2 | 09/07/16 attack 2 | 13/07/16 attack 2 | 07/01/18, 20/01/18 attack 4 | 04/12/18 attack 5 |
| White cell count (×109/L) | 4–10 | 7.04 | | | | | Neutrophils (%) | 45–75 | 65 | | | | | Lymphocytes (%) | 25–40 | 26 | | | | | Monocytes (%) | 2–10 | 7 | | | | | Eosinophils (%) | 1–6 | 2 | | | | | Basophils (%) | 0–2 | 0 | | | | | Red cell count (×1012/L) | 4.5–6.5 | 5.46 | | | | | Haematocrit (%) | 40–54 | 50.6 | | | | | Haemoglobin (g/dL) | 13–18 | 16.4 | | | | | Platelets (×109/L) | 150–400 | 369 | | | | | International normalised ratio (INR) | | | | | | 1.98 | Total bilirubin (umol/L) | 0–21 | 134.7 | 229.1 | 293.7 | | 393 | Direct bilirubin (umol/L) | 0–3.4 | 108.4 | 204.9 | 249.3 | | 337 | Alkaline phosphatase (U/L) | 52–171 | 288.5 | 313.0 | 370.0 | | 692 | Gamma glutamyl transferase (U/L) | 2–42 | 18.1 | 8.0 | 9.0 | | 12 | Aspartate aminotransferase (U/L) | 0–50 | 186.5 | 60.7 | 46.1 | | 48 | Alanine aminotransferase (U/L) | 0–50 | 400.4 | 62.4 | 43.7 | | 32 | Total protein (g/L) | 60–85 | | | | | 91 | Albumin (g/L) | 35–55 | | | | | 46 | Hepatitis B surface antigen | Negative | Negative | | | | Negative | Hepatitis A IgM antibody | Negative | Negative | | Negative | | Negative | Hepatitis A total antibody | Negative | | | Positive | | | Hepatitis C antibody | Negative | | Negative | | | Negative | Antinuclear antibody | | | | | Negative | | Antimitochondrial antibody | | | | | Negative | | Anti-LKM A± | | | | | Negative | | Liver antibodies | | | | | Negative | |
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±Antiliver kidney microsome type 1 antibody. ASMA, AMA-M2, M2-3E, SP-100, PML, gp210, LKM-1, LC-1, SLA/LP, and Ro-52. |